Tribromoethyl Alcohol, IC-03287177
Product Introduction
Tribromoethyl alcohol (2,2,2-tribromoethanol), also known as Avertin, is a halogenated alcohol compound widely used as a general anesthetic in laboratory animal research. It produces rapid, reliable, and reversible anesthesia with minimal cardiovascular and respiratory depression at appropriate doses. Tribromoethyl alcohol is commonly administered intraperitoneally to mice and other small rodents for short-to-medium duration surgical procedures, including stereotaxic surgery, embryo transfer, and various terminal or non-terminal experimental manipulations. Its advantages include ease of administration, rapid induction, good surgical plane maintenance, and predictable recovery. The compound is also used as a reagent in organic synthesis and as a preservative in pharmaceutical preparations.
Product Features
1. Laboratory Animal Anesthetic: Widely used for short-to-medium duration anesthesia in mice and small rodents.
2. Rapid Induction and Recovery: Produces reliable anesthesia with predictable recovery times.
3. Minimal Physiological Impact: At appropriate doses, causes limited cardiovascular and respiratory depression.
4. Ease of Administration: Typically administered intraperitoneally for convenient dosing.
5. High Purity: Supplied at 97% purity for reproducible experimental use.
Specifications
Size: 100 mg / 500 mg / 1 g / 1 mL (10 mM in DMSO) / 5 g
CAS Number: 75-80-9
Purity: 97%
Molecular Weight: 282.76
Molecular Formula: C2H3Br3O
Solubility: Ethanol: soluble; Water: slightly soluble; DMSO: soluble
Storage and Stability
Storage Conditions: Store at room temperature, sealed in dry conditions, and keep in a dark place. Protect from light and moisture.
Shelf Life: The product is stable for 36 months from the date of manufacture when stored as directed. For the 10 mM DMSO solution, store at -20¡æ protected from light.
Protocol (For Reference Only)
Important: Tribromoethyl alcohol is light-sensitive and should be protected from light. Prepare working solutions under sterile conditions. Avertin solutions should be prepared and stored properly to avoid degradation.
1. Working Solution Preparation for Anesthesia: Dissolve tribromoethyl alcohol in sterile water or saline with warming and stirring until completely dissolved. Typical working concentrations for mouse anesthesia range from 1.25-2.5% (w/v). Filter sterilize and store protected from light at 4¡æ for up to 1 week or aliquot and store at -20¡æ.
2. Anesthesia Administration: Administer intraperitoneally to mice at a dose of 240-400 mg/kg body weight (typically 0.5-0.8 mL of a 1.25-2.5% solution per 25 g mouse). Assess anesthesia depth by pedal reflex and respiratory rate.
3. Dose Adjustment: Adjust dose based on strain, age, and health status of animals. Older or debilitated animals may require lower doses.
4. Recovery: Following the procedure, place animals on a warming pad and monitor until fully recovered. Recovery typically occurs within 30-60 minutes.
5. Storage of Working Solution: Store prepared working solution at 4¡æ protected from light for up to 1 week. Do not use if precipitate or discoloration is observed.
Precautions
1. Protect from light and moisture during storage. Tribromoethyl alcohol degrades upon exposure to light and air.
2. Prepare working solutions under sterile conditions and filter sterilize before use.
3. Tribromoethyl alcohol is a potential irritant and should be handled with appropriate protective equipment.
4. Anesthesia depth should be carefully monitored to avoid overdose. Use appropriate controls and dose titration.
5. For research use only. Not for use in diagnostic or therapeutic procedures.
FAQ (Simplified)
Q1: What is the recommended dose for mouse anesthesia?
A1: A typical intraperitoneal dose is 240-400 mg/kg. For a 25 g mouse, this corresponds to approximately 0.5-0.8 mL of a 1.25-2.5% working solution. Adjust based on animal strain and condition.
Q2: How should I prepare the working solution?
A2: Dissolve tribromoethyl alcohol in sterile water or saline with warming and stirring, filter sterilize, and store protected from light at 4¡æ for up to 1 week.
Q3: How should tribromoethyl alcohol be stored?
A3: Store powder at room temperature sealed in dry conditions protected from light. The 10 mM DMSO solution should be stored at -20¡æ protected from light.
Disclaimer
1. For Research Use Only. Not for use in diagnostic or therapeutic procedures.
2. Due to the variable nature of animal experiments, dose optimization is recommended for specific species, strains, and procedures.
3. This warranty is limited to the replacement of the product. The manufacturer assumes no liability for incidental or consequential damages.
4. Wear appropriate protective clothing and gloves when handling this product.
Ordering Information
Catalog Number: IC-03287177
Product Name: Tribromoethyl Alcohol
Size: 100 mg / 500 mg / 1 g / 1 mL (10 mM in DMSO) / 5 g
Suggested Retail Price:
100 mg: CNY ¥450.00 / USD $45.00 / EUR €54.00 / JPY ¥8100.00
500 mg: CNY ¥540.00 / USD $54.00 / EUR €64.80 / JPY ¥9720.00
1 g: CNY ¥675.00 / USD $67.50 / EUR €81.00 / JPY ¥12150.00
1 mL (10 mM in DMSO): CNY ¥675.00 / USD $67.50 / EUR €81.00 / JPY ¥12150.00
5 g: CNY ¥1350.00 / USD $135.00 / EUR €162.00 / JPY ¥24300.00
Note: The specific price is subject to the transaction price in the offline contract. This document is provided for technical reference only and does not constitute any form of sales advertisement or invitation to offer. For product details and purchase inquiries, please contact local sales representatives.
