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Recombinant Human HER3/ErbB3 |
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Cat.No.: |
CYT-P21860 |
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Product Background |
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Recombinant Human HER3 |
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Receptor tyrosine-protein kinase erbB-3 is an enzyme that in humans is encoded by the ERBB3 gene. This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ERBB3 belongs to the protein kinase superfamily,tyr protein kinase family and EGF receptor subfamily.It contains 1 protein kinase domain and it is expressed in Epithelial tissues and brain. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. |
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Product Information |
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Source |
Human Cells |
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Molecular Weight |
69.5 KDa |
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AA Sequence |
Recombinant Human Receptor Tyrosine-Protein Kinase ErbB-3 is produced by our Mammalian expression system and the target gene encoding Ser20-Thr643 is expressed with a 6His tag at the C-terminus. |
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Biological Activity |
Loaded Human NRG1Beta (245AA)(C753) on APS Biosensor, can bind Human HER3-His(C00Y) with an affinity constant of 15 nM as determined in BLI assay. |
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Physical Appearance |
Supplied as a 0.2 ¦Ìm filtered solution of PBS, 50% Glycerol, pH7.4. |
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Formulation |
Supplied as a 0.2 ¦Ìm filtered solution of PBS, 50% Glycerol, pH7.4 |
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Endotoxin |
< 1 EU/µg as determined by LAL test |
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Reconstitution |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting. |
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Purity |
Greater than 95% as determined by reducing SDS-PAGE |
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Stability & Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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12 months from date of receipt, -20 to -70 ¡ãC as supplied. |
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1 month, 2 to 8 ¡ãC under sterile conditions after reconstitution. |
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3 months, -20 to -70 ¡ãC under sterile conditions after reconstitution. |
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Usage Information |
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This product is offered by InCellGen only for Scientific Research & Laboratory USE. NOT FOR OTHER USE. |
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Order Information |
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Cata.No. |
Quantity |
Price($) |
Price($) |
Price(£¤) |
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CYT-P21860 |
10ug |
$90.00 |
€99.00 |
£¤900.00 |
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CYT-P21860 |
50ug |
$180.00 |
€198.00 |
£¤1,800.00 |
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CYT-P21860 |
1mg |
$3,200.00 |
€3,520.00 |
£¤32,000.00 |
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Free Delivery on orders over $200.00. |
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We Devoted Ourselves To The Development Of Biomedical Research Reagent. |
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