CLF [Cholyl-Lys-Fluorescein]£¬IC-1569
Description
CLF is a fluorescein-labeled bile acid analog that closely parallels the cellular binding and uptake properties of cholic acid derivatives. It is a divalent ''''unipolar'''' anionic fluorescent monohydroxy bile salt analog with physical, biological and cholestatic properties that are similar to those of lithocholate, glycolithocholate and their derivatives and thus offers a potentially useful probe for studying mechanisms of monohydroxy bile salt-induced cholestasis at the hepatocellular level. CLF is currently used as a tool for the visualization of bile acid transport within liver tissue.
Storage Conditions
Freeze (<-15 ¡ãC), Minimize light exposure
Expiration Date
24 months upon receiving
Product Details
Appearance:Yellow solid
Molecular Weight:926.12
Soluble In DMSO
Ex/Em Wavelength
Excitation Wavelength£º498 nm
Emission Wavelength£º517 nm
Common stock solution preparation
Volume of DMSO needed to reconstitute specific mass of CLF [Cholyl-Lys-Fluorescein] to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.
|
|
0.1 mg |
0.5 mg |
1 mg |
5 mg |
10 mg |
|
1 mM |
107.977 µL |
539.887 µL |
1.08 mL |
5.399 mL |
10.798 mL |
|
5 mM |
21.595 µL |
107.977 µL |
215.955 µL |
1.08 mL |
2.16 mL |
|
10 mM |
10.798 µL |
53.989 µL |
107.977 µL |
539.887 µL |
1.08 mL |
