Reagent
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Reagent
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Antibody
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Primary Antibody
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Anti alpha SMA antibody£¬1062736
Click£º10036     Release date£º2019-5-6    Author£ºAdministrator    Source£ºOriginal
Anti alpha SMA antibody
Cata.No. 1062736
Host Mouse
Isotype IgG
Conjugation Unconjugated
Reactivity Human,Mouse,Rat,Bovine
Applacition WB 1:500-1:1000
IHC 1:50-1:500
IF/ICC 1:200
IP 1:100
CHIP N/A
ELISA N/A
Uniprot P62736 Western Blot; Sample: Lane1: Human Placenta lysate; Lane2: Porcine Heart£¬lysate; Lane3: Mouse Heart lysate 1/1000
Gene ID ACTA2(59)
Mass (Da) 42kD
Localization Cytoplasm>Cytoskeleton.
Storage  -20¡æ
Immunogen Recombinant  human ACTA2(Accession P62736) Ile167~Phe377 with N-terminal His Tag.
Alternative Names
a actin; AAT6; ACTA_HUMAN; ACTA2; Actin alpha 2 smooth muscle aorta; Actin aortic smooth muscle; Actin, aortic smooth muscle; ACTSA; ACTVS; Alpha 2 actin; Alpha actin 2; Alpha cardiac actin; Alpha actin-2; Cell growth inhibiting gene 46 protein; Cell growth-inhibiting gene 46 protein; GIG46; Growth inhibiting gene 46; MYMY5; Sarcomeric Actin.
BackGround
ACTA2 (also known as ¦Á-smooth muscle actin or ¦Á-SMA) belongs to the actin family. Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. ACTA2 is primarily expressed in vascular smooth muscle and anti-ACTA2 is commonly used to marker smooth muscle cells. This antibody may cross-react with other isoforms of actins.
Reference
1. Ota T, Suzuki Y, Isogai T, Sugano S. Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat Genet. 2004 Jan;36(1):40-5. 
2. Reddy S, Ozgur K, Kumar CC, Ruley HE. Structure of the human smooth muscle alpha-actin gene. Analysis of a cDNA and 5'''' upstream region. J Biol Chem. 1990 Jan 25;265(3):1683-7.
3. Kamada S, Kakunaga T. The nucleotide sequence of a human smooth muscle alpha-actin (aortic type) cDNA. Nucleic Acids Res. 1989 Feb 25;17(4):1767. 
Order Information
Cat./REF. Size Price($£© Price(€) Price(£¤/CNY£© Price(£¤/JYP£©
1062736 25ul $150.00  € 180.00 £¤1,500.00 £¤29,850.00
1062736 50ul $210.00  € 252.00 £¤2,100.00 £¤41,790.00
1062736 100ul $336.00  € 403.20 £¤3,360.00 £¤66,864.00




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