DOTA-NHS-ester, |
170908-81-3 |
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Cat.No.: |
IC-0172809 |
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Product Information |
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Biological Activity |
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DOTA-NHS-ester is a linker for affibody molecules and is applied in small animals PET, SPECT, and CT. DOTA-NHS-ester can be used to label radiotherapeutic agents or imaging probes for the detection of tumors[1]. |
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Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines) |
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Species |
Mouse |
Rat |
Rabbit |
Guinea pig |
Hamster |
Dog |
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Weight (kg) |
0.02 |
0.15 |
1.8 |
0.4 |
0.08 |
10 |
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Body Surface Area (m2) |
0.007 |
0.025 |
0.15 |
0.05 |
0.02 |
0.5 |
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Km factor |
3 |
6 |
12 |
8 |
5 |
20 |
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Animal A (mg/kg) = Animal B (mg/kg) multiplied by (Animal B Km / Animal A Km) |
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Order Information |
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Quantity |
Price($) |
Price($) |
Availability |
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5mg |
$300.00 |
€330.00 |
In stock |
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10mg |
$400.00 |
€440.00 |
In stock |
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50mg |
$900.00 |
€990.00 |
In stock |
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Free Delivery on orders over $350.00. |
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Chemical Information |
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Molecular Weight |
501.49 |
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Formula |
C20H31N5O10 |
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CAS Number |
170908-81-3 |
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Purity |
>98% |
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Solubility |
DMSO: 50 mg/mL (99.70 mM) |
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Storage |
at -20¡ãC |
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Reference |
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[1]. Hoppmann S, et al. Radiolabeled affibody-albumin bioconjugates for HER2-positive cancer targeting.Bioconjug Chem. 2011 Mar 16;22(3):413-2 |
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We Devoted Ourselves To The Development Of Biomedical Research Reagent. |